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An unparalleled longevity serum that visibly reverses the look of skin age – restoring firmness, smoothness & radiance for a younger look, longer.
The discount offer isn't valid for this new product.
Clinically shown to help skin look up to 8 years younger*
100% said skin looked more youthful, vibrant & firmer after only 3 weeks of use**
Lightweight, silky treatment serum visibly targets 12 key signs linked to the root causes of ageing
Future Proof Your Skin
Clinically proven to visibly reverse the look of skin age, this next-gen longevity serum delivers firmer, smoother, more radiant skin now – while future-proofing your skin’s tone, texture and long-term resilience.
Backed by 5 years of research and powered by NAD⁺ supporting age-disrupting technology – including taurine, exosomes and peptides – CellularYouth Longevity Serum helps recharge the natural energy and repair pathways that can fade with age, so skin visibly mirrors the vitality and renewal of younger skin.
Think of your skin like a battery. As cellular energy declines, natural renewal slows – accelerating ageing’s timeline. This breakthrough formula visibly slows 12 signs of ageing, helping extend skin’s visible healthspan and support a younger-looking biological skin age, longer.
*Supplier clinical study. Skin appeared up to 8 years younger after 42 days. Results may vary.
**Based on a consumer-perception study with 33 people ages 18-69.
Because skincare works best when it suits your skin type.
Wash your face with a gentle cleanser and wait 15-30 minutes. Select what you see and how you feel.
Sunflower Sprout ExtractSupports natural energy pathways to help sustain skin’s youthful vitality, longer.
Goji Phyto-ExosomesVisibly tightens contours, reduces the look of fine lines & strengthens skin barrier.
Acetyl-Tetrapeptide-2AI-made signal peptide promotes renewal for smoother, firmer & more radiant skin.
How to use a serum
After cleansing, toning and exfoliating, apply 1-2 drops to the face and neck once or twice daily. Do not rinse. Follow with another treatment and/or moisturiser. For AM, always follow with a moisturiser containing a broad-spectrum SPF 30 or higher.
Most anti-ageing products target visible signs AFTER they appear – and mostly at the surface. Paula’s Choice wanted to change that. We developed a clinically proven formula based on the latest longevity research to help slow visible skin changes caused by time. The result: a breakthrough serum for all skin types that supports skin’s natural renewal and repair processes, helping maintain youthful vitality longer.
The CellularYouth Longevity Serum supports skin’s energy and renewal pathways with NAD-supporting technology and biotech actives that help revitalise the look of tired skin and promote radiance and resilience over time.
Developed after five years of longevity science research, this breakthrough serum is clinically tested to improve multiple visible signs of ageing like radiance, tone and wrinkles – by addressing age-related skin fatigue. What sets it apart is a powerhouse blend of NAD-supporting technology, a next-generation AI-designed peptide, and plant-based goji phyto-exosomes. Together, these advanced ingredients optimise skin function in ways traditional anti-ageing serums can’t. This is the first Paula’s Choice product that empowers you to take control of your skin’s time-related changes, something once thought impossible.
This serum is for anyone who wants a powerful treatment to help reverse visible signs of ageing, restore skin’s vitality and slow future changes. It’s not limited to one age group – the formula is designed for every stage of your skin journey. Whether you’re already seeing signs of ageing or simply want to maintain youthful resilience, it delivers what your skin needs now and in the future.
The formula is dermatologist-tested and suitable for sensitive skin. Its barrier-supporting ingredients help reinforce skin’s resilience, which can benefit sensitive or redness-prone skin with consistent use.
No, this serum does not contain fragrance, dyes or parabens. Yes, it is vegan.
The colour comes from a combination of mineral pigments (iron oxides, titanium dioxide) and vitamin B12 (cyanocobalamin).
It refers to ingredients that help your skin maintain its natural energy cycle. In simple terms, these ingredients support the process that regenerates NAD⁺ which is a coenzyme essential for skin vitality by activating NAMPT, often called the skin’s “charging station.” This helps keep skin looking energised, healthy and resilient.
This serum can be used by adults of any age but is especially beneficial for those noticing or wanting to prevent visible signs of cellular ageing due to the passage of time.
Yes, the ingredients in the CellularYouth Longevity Serum are considered safe for use during pregnancy or while breastfeeding. If you’re uncertain about starting a new product or a combination of ingredients while pregnant or breastfeeding, consult your GP and follow their advice.
There aren't any specific skincare ingredients known to be incompatible with this serum. The formula can be layered with many other beneficial ingredients such as vitamin C, retinoids, peptides, niacinamide and more.
TNAD-supporting ingredients, like those in our CellularYouth Longevity Serum, help promote skin’s natural energy and renewal processes. Retinoids, peptides and vitamin C target different aspects of visible ageing, such as improving surface texture, firmness and brightness. Together, they work synergistically to support healthier-looking, more resilient skin.