Spermidine

Bueno

Antioxidante

Spermidine at a glance

  • Natural compound in plants, fungi and animals
  • Has potential to regulate aspects of aging skin
  • Proven to deliver skin-soothing benefits
  • May mitigate the appearance of hypopigmentation
  • More research related to topical application is needed

Spermidine description

Spermidine is a naturally occurring compound found in plants, fungi and animals (including humans). It has emerged as a promising ingredient linked to longevity due to its significant role in autophagy, a cellular recycling process responsible for regulating key aspects of aging and health. While current research focuses heavily on oral supplementation and medicinal applications, spermidine shows intriguing potential as an anti-aging skin care ingredient as well. One of the more unique areas of scientific exploration regarding spermidine is its ability to help even out hypopigmentation (diffused or localized patches of skin that appear lighter). Studies also suggest spermidine can strengthen skin’s natural protective barrier, provide collagen support and deliver skin-soothing benefits. Beyond skin benefits, research indicates spermidine has benefits for supporting hair and nail growth when taken in supplement form. While more studies are required to fully understand spermidine’s efficacy in skin care products, the available evidence looks promising. We’ll continue to watch this space and update. Spermidine is typically sourced from plant-based materials like wheatgerm and can be found in relatively high levels in dietary foods such as soybeans (especially a fermented version known as natto) and mushrooms. Note: Cosmetic use of spermidine may be restricted in certain global markets.

Spermidine references

  • CCIH, Accessed October 2024, ePublication
  • Aesthetic Plastic Surgery, May 2024, ePublication
  • International Journal of Molecular Sciences, March 2023, pages 1-25
  • Comprehensive Reviews in Food Science and Food Safety, May 2022, pages 2,820-2,842
  • GeroScience, April 2021, pages 673-690
  • Communications Biology, February 2021, pages 1-11
  • Applied Sciences, June 2020, pages 1-12
  • Dermatology Practical & Conceptual, October 2017, pages 17-21
  • Gerontology, January 2014, pages 319-326
  • Journal of Investigative Dermatology, February 1996, pages 249-253

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Calificaciones de ingredientes

Excelente

Ingrediente sobresaliente con beneficios reales para la piel. Su eficacia está demostrada y respaldada por estudios independientes.

Bueno

Aunque no son tan beneficiosos como los de la categoría excelente, suelen ser necesarios para mejorar la textura, la estabilidad o la absorción de una fórmula.

Aceptable

Puede presentar ciertas limitaciones en cuanto a su apariencia, estabilidad o eficacia. A veces, son ingredientes básicos o que no cuentan con suficiente respaldo científico.

Poco recomendable

Aunque puede ofrecer algunos beneficios se recomienda evitarlo por su probabilidad de causar irritación, especialmente si se combina con otros ingredientes problemáticos.

Desaconsejable

Ha demostrado provocar efectos adversos como irritación, inflamación o sequedad, especialmente si se utiliza en altas concentraciones o junto con otros ingredientes irritantes.

Desconocido

No hemos encontrado este ingrediente en nuestro diccionario. Registramos todos los ingredientes desconocidos y actualizamos la información de forma continua.

Sin calificar

Ingrediente registrado, pero con la información científica disponible pendiente de revisar.