Palmitoyl Hexapeptide-12

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Péptidos

Palmitoyl Hexapeptide-12 at a glance

  • A synthetic peptide that matches a sequence of amino acids found in skin
  • Signals skin to look younger by boosting its firm feeling
  • Creates a supple surface by strengthening skin’s barrier
  • Requires a surprisingly low amount for efficacy

Palmitoyl Hexapeptide-12 description

Palmitoyl hexapeptide-12 is a lab-made peptide that blends the fatty acid palmitic acid with several amino acids, including glycine, histidine, and lysine. Combining this specifically engineered peptide with palmitic acid enhances its penetration into skin as well as the peptide’s stability. In the early days of peptides in skin care it went by the catchall term palmitoyl oligopeptide. The amino acid sequence of this peptide mimics that of peptides naturally occurring in skin, meaning skin recognises and can readily utilize it. It works on and within skin’s uppermost layers by influencing key supportive elements in skin that result in a firmer surface and minimized appearance of wrinkles. It also strengthens skin’s barrier by improving moisture retention, leaving skin feeling supple instead of rough. As a signal peptide, it can “tell” skin to look younger. It is considered safe as used in cosmetics, where its calculated efficacy is in the parts per million range. This translates to very low percentages used in skin care, as low as 0.0000001%; however, research is clear that small amounts of this peptide can produce impressive results. Palmitoyl hexapeptide-12 is most often used on its own rather than being part of a blend with other peptides, although such blends are available.

Palmitoyl Hexapeptide-12 references

  • Frontiers in Chemistry, October 2020, ePublication
  • International Journal of Toxicology, 2018, pages 90S-102S
  • Cosmetics, Volume 4, Issue 16, May 2017, pages 1–17
  • Tissue Engineering and Regenerative Medicine, February 2017, pages 73–80
  • Biomolecules and Therapeutics, July 2014, pages 321–327
  • International Journal of Cosmetic Science, June 2005, pages 155–160

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Calificaciones de ingredientes

Mejor

Probado y respaldado por estudios independientes. Ingrediente activo excepcional para la mayoría de los tipos de piel o problemas.

Bueno

Necesario para mejorar la textura, estabilidad o penetración de una fórmula.

Promedio

Generalmente no irritante, pero puede presentar problemas de aspecto, de estabilidad u otros que limiten su utilidad.

Malo

Hay probabilidad de irritación. El riesgo aumenta cuando se combina con otros ingredientes problemáticos.

Peor

Puede causar irritación, inflamación, sequedad, etc. Puede ofrecer algún beneficio en cierta medida, pero en general, se ha comprobado que causa más daño que beneficio.

Desconocido

No pudimos encontrarlo en nuestro diccionario de ingredientes. Registramos todos los ingredientes que faltan y realizamos actualizaciones continuas.

No calificado

Aún no hemos calificado este ingrediente porque no hemos tenido la oportunidad de revisar las investigaciones existentes sobre él.