Dipalmitoyl Hydroxyproline

Excellente

Péptidos

Dipalmitoyl Hydroxyproline at a glance

  • An oil-soluble derivative of hydroxyproline
  • Hydroxyproline is the primary amino acid in skin’s collagen
  • Helps preserve skin’s supportive elements
  • The palmitoyl portion comes from hydrating palmitic acid

Dipalmitoyl Hydroxyproline description

Dipalmitoyl hydroxyproline is an oil-soluble version of hydroxyproline, which is the primary amino acid in collagen. Making it oil-soluble improves penetration into skin and lips, where it works to signal skin from the uppermost layers to repair its supportive elements, leading to fewer visible lines and wrinkles. In essence, hydroxyproline is considered a signal peptide. This ingredient works best when paired with oils or glycols since both increase its affinity for skin. Along with supporting skin’s collagen, it also offsets collagen-degrading enzymes known as matrix metalloproteinases. When these enzymes proliferate unchecked, collagen is weakened, leading to signs of sagging and thinning lips. The recommended usage level of dipalmitoyl hydroxyproline is 0.1-2%; clinical studies from suppliers have shown measurable improvement of wrinkle depth when used at 0.5%. Palmitic acid is considered safe for skin, as are proline and hydroxyproline since the latter two are found naturally in skin and its collagen.

Dipalmitoyl Hydroxyproline references

  • International Journal of Toxicology, Volume 36, Supplement 3, November-December 2017, pages 51S-129S
  • International Journal of Cosmetic Science, April 2013, pages 156-162
  • The Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Calificaciones de ingredientes

Excelente

Ingrediente sobresaliente con beneficios reales para la piel. Su eficacia está demostrada y respaldada por estudios independientes.

Bueno

Aunque no son tan beneficiosos como los de la categoría excelente, suelen ser necesarios para mejorar la textura, la estabilidad o la absorción de una fórmula.

Aceptable

Puede presentar ciertas limitaciones en cuanto a su apariencia, estabilidad o eficacia. A veces, son ingredientes básicos o que no cuentan con suficiente respaldo científico.

Poco recomendable

Aunque puede ofrecer algunos beneficios se recomienda evitarlo por su probabilidad de causar irritación, especialmente si se combina con otros ingredientes problemáticos.

Desaconsejable

Ha demostrado provocar efectos adversos como irritación, inflamación o sequedad, especialmente si se utiliza en altas concentraciones o junto con otros ingredientes irritantes.

Desconocido

No hemos encontrado este ingrediente en nuestro diccionario. Registramos todos los ingredientes desconocidos y actualizamos la información de forma continua.

Sin calificar

Ingrediente registrado, pero con la información científica disponible pendiente de revisar.