Ceramide AP

Best

Emoliente

Ceramide AP at a glance

  • Naturally occurring, long chains of lipids (fats) that make up 16% of skin’s composition
  • Known to improve barrier strength, hydration, and suppleness when used as a skin care ingredient
  • Works optimally when combined with other ceramides + fatty acids and cholesterol
  • Deemed a safe cosmetic ingredient by the Cosmetic Ingredient Review Expert Panel

Ceramide AP description

Ceramide AP (AP stands for α-hydroxy-N-stearoylphytosphingosine) belongs to a larger group of ceramides that are naturally occurring, long chains of lipids (fats) in skin. To put it into perspective, skin’s general composition of ceramides is around 50% and of that, 16% of those ceramides are of the AP variety. Decreased levels of ceramides have been shown to weaken the barrier, making skin more vulnerable to external stressors. More specifically, a decline in ceramide AP has been linked to skin conditions such as eczema and psoriasis. Topical application of ceramide AP via skin care formulas can step in to help fill this gap and strengthen skin’s barrier against external stimuli. In general, ceramides work best when they’re combined with other replenishing ingredients like fatty acids and cholesterol. These lipid mixtures work in multiple ways to improve skin’s hydration, texture, and suppleness. Ceramides within skin also play a vital role in maintaining skin health since they signal other processes that keep things orderly. The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practises of use. Their survey data looked at personal care products containing concentrations between 0.00005-0.2% of ceramide AP. Ceramides used in skin care are typically created synthetically but can also be sourced naturally from plants.

Ceramide AP references

  • International Journal of Toxicology, 2020, pages 5S-25S  
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483 
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184 
  • Pharmaceutical Research, November 2012, pages 538-551
  • Journal of Lipid Research, July 2008, pages 1,466-1,476 
  • Journal of Lipid Research, September 2007, pages 1936-1943 
  • American Journal of Clinical Dermatology, 2003, pages 107-129 
  • Journal of Investigative Dermatology, November 2001, pages 1,126-1,136 
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Calificaciones de ingredientes

Mejor

Probado y respaldado por estudios independientes. Ingrediente activo excepcional para la mayoría de los tipos de piel o problemas.

Bueno

Necesario para mejorar la textura, estabilidad o penetración de una fórmula.

Promedio

Generalmente no irritante, pero puede presentar problemas de aspecto, de estabilidad u otros que limiten su utilidad.

Malo

Hay probabilidad de irritación. El riesgo aumenta cuando se combina con otros ingredientes problemáticos.

Peor

Puede causar irritación, inflamación, sequedad, etc. Puede ofrecer algún beneficio en cierta medida, pero en general, se ha comprobado que causa más daño que beneficio.

Desconocido

No pudimos encontrarlo en nuestro diccionario de ingredientes. Registramos todos los ingredientes que faltan y realizamos actualizaciones continuas.

No calificado

Aún no hemos calificado este ingrediente porque no hemos tenido la oportunidad de revisar las investigaciones existentes sobre él.