Allantoin

Excellente

Extractos vegetales

Allantoin at a glance

  • Occurs naturally in most organisms but can be produced synthetically
  • Has both soothing and moisturising properties for skin
  • Helps mitigate skin’s response to more active ingredients
  • Used in concentrations up to 2% in cosmetics

Allantoin description

Allantoin is a byproduct of uric acid that can be extracted from urea and is the result of metabolic processes that occur in most organisms - among them animals (including humans) and bacteria. It can also be extracted from comfrey (taken from the roots and leaves) and is proven safe and effective because it does not contain the potentially irritating alkaloid compounds that occur in the comfrey plant. Despite the natural source of allantoin being safe, the type of allantoin used in skin care products is generally produced synthetically as this guarantees no impurities while sacrificing none of allantoin’s effectiveness. It serves as an effective soothing agent and has moisturising properties, giving it value especially in products designed to treat sensitive or compromised skin. It can also help mitigate skin’s response to stronger active ingredients and is often included in formulas to help buffer any potential adverse effects. In cosmetics, it is used in concentrations up to 2%, but in clinical settings it can be used in greater amounts, where research has shown it can have an impact on healing. In the United States, it is FDA-approved as an over the counter (OTC) skin protectant in concentrations of 0.5-2%.

Allantoin references

  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=347&showFR=1

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Calificaciones de ingredientes

Excelente

Ingrediente sobresaliente con beneficios reales para la piel. Su eficacia está demostrada y respaldada por estudios independientes.

Bueno

Aunque no son tan beneficiosos como los de la categoría excelente, suelen ser necesarios para mejorar la textura, la estabilidad o la absorción de una fórmula.

Aceptable

Puede presentar ciertas limitaciones en cuanto a su apariencia, estabilidad o eficacia. A veces, son ingredientes básicos o que no cuentan con suficiente respaldo científico.

Poco recomendable

Aunque puede ofrecer algunos beneficios se recomienda evitarlo por su probabilidad de causar irritación, especialmente si se combina con otros ingredientes problemáticos.

Desaconsejable

Ha demostrado provocar efectos adversos como irritación, inflamación o sequedad, especialmente si se utiliza en altas concentraciones o junto con otros ingredientes irritantes.

Desconocido

No hemos encontrado este ingrediente en nuestro diccionario. Registramos todos los ingredientes desconocidos y actualizamos la información de forma continua.

Sin calificar

Ingrediente registrado, pero con la información científica disponible pendiente de revisar.